Irf1 molecular weight

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August undefined, 2024

WebDescription Product name Recombinant Human IRF1 protein (His tag) Purity > 90 % SDS-PAGE. NULL Endotoxin level < 1.000 Eu/µg Expression system Escherichia coli Accession …

Molecular characterization of the interferon regulatory factor (IRF ...

WebJun 19, 2024 · This observation was further corroborated by molecular studies showing increased percentages of IL-17A/IFN-γ-producing CD4 + T cells in the central nervous … WebSep 29, 2024 · Given that IRF-1 is well known to molecularly act downstream of IFN-γ signaling, we also subjected mice lacking IFN-γ to C. rodentium infection. However, compared to control mice, we observed no... biohealthcare

Expression of interferon regulatory factor (IRF) genes and

WebUse a concentration of 0.1 - 0.5 µg/ml. Predicted molecular weight: 36 kDa. ICC Use a concentration of 0.5 - 1 µg/ml. IHC-P ... Defects in IRF1 are a cause of gastric cancer (GASC) [MIM:613659]; also called gastric cancer … WebMay 5, 2014 · Interleukin 1 (IL-1) is a pleiotropic cytokine that regulates immune and inflammatory responses by inducing the expression of a variety of pro-inflammatory cytokines and chemokines. WebAnalysis of peripheral blood leucocytes from 25 normal individuals showed that the IRF1:IRF2 ratio varied between 1.13 and 2.30 (mean +/- s.d. 1.49 +/- 0.33). Similar values were obtained for normal bone marrow specimens, with no significant difference between CD34+ and CD34- cells. daily free bet offers

Interferon regulatory factor 1 (IRF-1) promotes intestinal group 3 ...

Molecular cloning and functional analysis of polymeric

WebMolecular function Cellular component: Biological process ... Interferon regulatory factor 1 is a protein that in humans is encoded by the IRF1 gene. ... Body weight: Normal Anxiety: Normal Neurological assessment: Normal Grip strength: Normal Hot plate: Normal Dysmorphology: WebMar 21, 2024 · IRF1 (Interferon Regulatory Factor 1) is a Protein Coding gene. Diseases associated with IRF1 include Lung Cancer and Gastric Cancer. Among its related pathways are Bacterial infections in CF airways and Overview of interferons-mediated signaling … HBB (Hemoglobin Subunit Beta) is a Protein Coding gene. Diseases associated with … Gene Ontology (GO) - Molecular Function for MET Gene. GO ID Qualified GO term … VCAM1 (Vascular Cell Adhesion Molecule 1) is a Protein Coding gene. Diseases … Complete information for IWS1 gene (Protein Coding), Interacts With SUPT6H, … PHGDH (Phosphoglycerate Dehydrogenase) is a Protein Coding gene. Diseases … CCL2 (C-C Motif Chemokine Ligand 2) is a Protein Coding gene. Diseases … IFITM1 (Interferon Induced Transmembrane Protein 1) is a Protein Coding gene. … CCL19 (C-C Motif Chemokine Ligand 19) is a Protein Coding gene. Diseases … IGFBP7 (Insulin Like Growth Factor Binding Protein 7) is a Protein Coding gene. … CDKN1B (Cyclin Dependent Kinase Inhibitor 1B) is a Protein Coding gene. Diseases … daily freebie forumWebDec 1, 2024 · The predicted molecular weight of the Cf IRF1 protein was approximately 40 kDa. Using the SMART program and NCBI conserved domain search program, the N-terminus of the Cf IRF1 protein was predicted to encode an IRF1 domain, similar to IRF1 family proteins of other species ( Fig. 2 A ). Download : Download high-res image (2MB) biohealth corretora

"WebInterferon regulatory factor 1 (IRF1) is a tumor suppressor gene often found downregulated in breast cancers; this low expression correlates with endocrine therapy resistance (Bouker et al., 2004, 2005, 2007; Gu et al., 2002 ). Approximately, 30% of cancerous breast lesions have allelic loss of IRF1 when compared with the adjacent normal breast ... " - Irf1 molecular weight

Irf1 molecular weight

Expression of interferon regulatory factor (IRF) genes and

WebIRF1 as a transcriptional regulator which displays a remarkable functional diversity in the regulation of cellular responses. The calculated molecular weight of IRF1 is 37 kDa, but … WebSep 16, 2024 · Retained uremic toxins can be divided into three groups according to physicochemical characteristics: small water-soluble compounds (molecular weight (MW) < 500 Da), middle-molecules (500 Da <...

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WebIRF1 Protein Molecular Weight & PI . The parameters have been computed for the following feature . FT CHAIN 1-325 Interferon regulatory factor 1. Molecular weight (Da) 36502.21 Theoretical pI . 5.22 Bulk Order of Recombinant IRF1 Protein . Please Leave Us a Message if you have any questions regarding bulk price quote of our products on the ... WebApr 10, 2024 · The predicted theoretical isoelectric point of pIgR amino acid sequence is 5.92, and theoretical molecular weight is 37.48 kDa, and the first 19 amino acids are signal peptides. It is predicted that there may be an N-linked glycosylation site (N 34 LTV) in the extracellular domain (Fig. 1). Download : Download high-res image (4MB)

WebObjectives: Although it has been reported that Interferon regulatory factor 1 (IRF1) inhibits Mycobacterium tuberculosis (Mtb) infection via inducible nitric oxide synthase (iNOS) in mice, how it counteracts with mycobacterial infection in human remains largely obscure. WebWestern blot analysis of HeLa cells, untreated or treated with Human Interferon-γ (hIFN-γ) #8901 (100 ng/ml, 4 hr), using IRF-1 (D5E4) XP ® Rabbit mAb. Western blot analysis of …

WebJan 15, 2024 · Molecular and functional characterization of interferon regulatory factor 1 (IRF1) ... 10 μg/g body weight] for 3 h, whose spleen and kidney were used for the extraction of total RNA by using Trizol Reagent (Invitrogen). The first-strand cDNA was synthesized from above total RNA and served as template to amplify ORF sequence of Xt-IRF1 by PCR ... WebIRF1 Antibodies. Antibodies that detect IRF1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunoprecipitation, Immunocytochemistry and Flow Cytometry. These antibodies target IRF1 in Human, Mouse and Rat samples. Our IRF1 polyclonal, recombinant monoclonal and monoclonal antibodies are developed ...

WebMar 29, 2024 · IRF1 and IRF2 also appear to be important in regulating DC subset development— Irf −/− mice show a loss of splenic and epidermal DCs (due to augmented type I IFN signaling) ( 109, 110) whereas Irf1−/− exhibit an increase in pDCs and a decrease in CD8 + DCs in mice, along with an increase of IL-10 and TGF-β ( 111 ).

WebReference #: P10914 (UniProtKB) Alt. Names/Synonyms: Interferon regulatory factor 1; IRF-1; IRF1; MAR Gene Symbols: IRF1 Molecular weight: 36,502 Da Basal Isoelectric point: 5.22 Predict pI for various phosphorylation states Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® daily free books todayWebJul 8, 2024 · IRF1 expression is associated with the expression of IFNβ, which leads to the activation of the JAK-STAT pathway. ... Consistently, molecular function enrichment … daily free coins monopoly slotshttp://antibodysystem.com/product/3227.html daily free bag patternWebIRF1-regulated gene expression equipped low-grade PDAC cells with distinctive properties related to antigen presentation and processing as well as responsiveness to IFN stimulation. daily free books ukWebDisruption of this signaling pathway by deletion of Irf1 or Stat1 protects mouse macrophages from TNF-α- and IFN-γ- induced cell death, as well as induced holopsia deletion in the absence of Irf1. Similarly, Stat1-/- mice were protected from TNF- and IFN-γ- induced death. Figure 4. TNF-α and IFN-γ induce JAK/STAT1/IRF1 signaling and PANoptosis biohealth congressWebDec 27, 2024 · Results: IRF1 was identified as a novel TF that suppresses KPNA2 gene expression. We observed that IRF1 expression was lower in cancerous tissues than in normal lung tissues and that its low expression was correlated with poor prognosis in … bio healthcare conferenceWebApr 4, 2024 · IRF-1 is an important signaling protein in the interferon pathway. It not only activates gene expression as a transcription factor, but may perpetuate disease by leading to a dysregulated epigenome. Data suggest that interferon regulatory factors 1 and 2 (IRF1 and IRF2) may serve as potential targets of therapy. biohealth collagen